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Isotonix OPC-3®
sku C13009
$101.68 CAD
$2.03 CAD Cashback
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Benefits
- Antioxidant for the maintenance of good health
- Contains isotonic-capable Pycnogenol® , renowned for its extensive clinical research with more than 120 studies published in peer-reviewed medical journals
- Also contains Red Wine Extract, Grape Seed Extract, Bilberry Extract, and Citrus Extract (Bioflavonoids)
- Studies have shown OPCs to be many times more powerful than vitamin C and vitamin E
![Benefits](https://images.shop.com/pim/C13009/image_b/Pycnogenol_Info_CAN.jpg)
Product Classifications
Gluten-Free - The finished product contains no detectable gluten (<10ppm gluten)
No Detectable GMOs - The finished product contains no detectable genetically-modified organisms
Vegan - The product is made without ingredients produced by or derived from animals
Isotonic-Capable Drinkable Supplements - Easy-to-swallow supplements in liquid form are immediately available to the body for absorption
Quality Standards - GMP Operations and Standardised Ingredients
Checked For: Heavy Metals, Microbiological Contaminants, Allergens, Potency, Purity and Identity
Details
Isotonix OPC-3 is an isotonic-capable food supplement that is made from a combination of bilberry, grape seed, red wine, pine bark extracts and citrus extract bioflavonoids. Isotonix OPC-3 contains isotonic-capable Pycnogenol®, renowned for its extensive clinical research with more than 120 studies published in peer-reviewed medical journals.
Oligomeric proanthocyanidins (OPCs) are bioflavonoids (complex organic plant compounds) found in fruits, vegetables and certain tree barks that provide exceptional nutritional benefits to the human body. Studies have shown OPCs to be many times more powerful than vitamin C and vitamin E. Isotonix OPC-3 contains OPCs from grape seed extract, red wine extract, bilberry extract, Pycnogenol® from pine bark and citrus fruit. Our grape seed extract is a superior source of OPC, containing 92 percent of active ingredients with pine bark containing 84 percent of active OPC ingredients. The red wine extract contains flavonoids called leucocyanidins from the skin of red grapes. These are the three best sources of oligomeric proanthocyanidins available. Over 20,000 different flavonoids have been discovered, of which a select few are water-soluble and easily absorbed by the body. Isotonix OPC-3 contains the top three of the most bioavailable and potent forms of OPCs. Pycnogenol in Isotonix OPC-3 is the most clinically researched and potent bioflavonoid.
Isotonic, which means "same pressure," bears the same chemical resemblance of the body's blood, plasma and tears. All fluids in the body have a certain concentration, referred to as osmotic pressure. The body's common osmotic pressure, which is isotonic, allows a consistent maintenance of body's tissues. In order for a substance to be absorbed and used in the body's metabolism, it must be transported in isotonic fluids.
Isotonix dietary supplements are delivered in a solution similar in constitution to the body's own naturally produced isotonic fluids. This similarity of pH and osmotic pressure means that the body has less work to do in order to convert the solution into a state ready for maximum absorption — greatly decreasing the amount of time and work necessary to absorb a supplement. The isotonic state of the suspension allows nutrients to pass into the small intestine and be effectively absorbed into the blood stream. With Isotonix products, little nutritive value is lost, making the absorption of nutrients highly efficient while delivering maximum results.
Pycnogenol is registered in the US.
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Isotonix Delivery System
![Isotonix Delivery System](https://images.shop.com/pim/C13009/image_h/C13009_OPC3.jpg)
Isotonic, which means "same pressure," bears the same chemical resemblance of the body's blood, plasma and tears. All fluids in the body have a certain concentration, referred to as osmotic pressure. The body's common osmotic pressure, which is isotonic, allows a consistent maintenance of body's tissues. In order for a substance to be absorbed and used in the body's metabolism, it must be transported in isotonic fluids. Isotonix dietary supplements are delivered in a solution similar in constitution to the body's own naturally produced isotonic fluids. This similarity of pH and osmotic pressure means that the body has less work to do in order to convert the solution into a state ready for maximum absorption — greatly decreasing the amount of time and work necessary to absorb a supplement. The isotonic state of the suspension allows nutrients to pass into the small intestine and be effectively absorbed into the blood stream. With Isotonix products, little nutritive value is lost, making the absorption of nutrients highly efficient while delivering maximum results.
Why the Isotonix® Delivery System is Great!
Ingredients
Grape Seed Extract
Grape seed extract is typically extracted from the seeds of red grapes (instead of white), which have a high content of compounds known as oligomeric proanthocyanidins. Grape seed extract is extremely rich in polyphenols, a compound high in antioxidants. Grape seed extract has even been found to promote healthy cholesterol levels.
Red Wine Extract
Red wine extract contains rich beneficial active ingredients. This extract is found in grape vines, roots, seeds and stalk, with its highest concentration in the skins. In the late 1990s, scientists took note of a phenomenon among the French. There were very low rates of heart disease in the provinces where residents consistently ate high fat foods and drank red wine. Scientists concluded that the protective properties of red wine have helped the French maintain heart health for years and subsequent scientific studies have further proven the fact that the OPCs found in red wine are greatly beneficial to maintain general well-being.
Pine Bark Extract (Pycnogenol®)
Pycnogenol is a natural plant extract from the bark of the maritime pine tree, which grows exclusively along the coast of southwest France in Les Landes de Gascogne. This unspoiled and natural forest environment is the unique source of pine bark. Pycnogenol represents a natural combination of genetically programmed constant proportions of procyanidins, bioflavonoids and organic acids.
Pine bark extract (Pycnogenol®) is a powerful antioxidant. As one of the most potent natural scavenger of free radicals, Pycnogenol combats many aggressive free radicals before they cause oxidative stress to vital organs. It has super-antioxidant capabilities.
Bilberry Extract
Bilberry extract is derived from the leaves and berry-like fruit of a common European shrub closely related to the blueberry. Extracts of the ripe berry are known to contain flavonoid pigments known as anthocyanins, powerful antioxidants. Scientific studies confirm that bilberry extract supports healthy vision and venous circulation. Bilberry extract helps maintain healthy circulation by strengthening capillaries, arteries and veins.
Citrus Extract (Bioflavonoids)
Bioflavonoids are found in certain plants to act as light filters protecting the delicate DNA chains and other important macromolecules by absorbing ultraviolet radiation. They have been found to promote cardiovascular health and help maintain healthy circulation by strengthening capillaries, arteries and veins.
![Ingredients](https://images.shop.com/pim/C13009/image_c/C13009_Alt1.jpg)
FAQs
What is Isotonix OPC-3?
Isotonix OPC-3 is a dietary supplement that bears some of the most powerful bioflavonoids currently known to research scientists. These bioflavonoids are scientifically termed oligomeric proanthocyanidins, commonly abbreviated OPCs. The purest and best-researched OPCs chosen for OPC-3 are prepared from grape seed, red wine, bilberries, Pycnogenol from pine bark and citrus fruit. This combination of powerful OPCs is unique to OPC-3, as is the Isotonix® delivery system, which enables rapid and highly efficient absorption of the OPCs.
What is a bioflavonoid?
Bioflavonoids are complex organic plant compounds. Plants and fruits differ in colors based on the specific bioflavonoids they contain. An increasing number of clinical studies have shown how bioflavonoids support health. Bioflavonoids found in OPCs play a key role in cardiovascular health and maintaining vascular integrity. Bioflavonoids have been shown to demonstrate support for healthy circulation and cell vitality. Normal collagen renewal is promoted, which supports firmness of the skin, joint cartilage and connective tissue.
What sets Isotonix OPC-3 apart from other bioflavonoid products?
Isotonix OPC-3 offers scientifically supported OPCs, found to be the most powerful antioxidants for human health. In addition to being powerful antioxidants, these individual OPCs have been shown to provide a myriad of specific health benefits. This science-driven selection of OPCs is unique to OPC-3, as is the Isotonix delivery system, which enables rapid and highly efficient absorption of the OPCs. The potent nutrients, in combination with the highly effective delivery system, makes OPC-3 the most powerful free radical scavenging product available.
Is Isotonix OPC-3 safe?
Yes. OPCs are among the most valuable constituents of a healthy human diet. OPCs have been researched and used for over 30 years throughout Europe. OPC-3 contains pure OPCs in combination with carefully balanced quantities of potassium and fructose/glucose, which set up the isotonic delivery system. OPC-3 is free of harmful chemicals, preservatives and alcohol. OPC-3 should be taken as directed.
How long does it take to benefit from Isotonix OPC-3?
Many effects of OPC-3 start to work after a single serving. Studies with human volunteers have found that the health benefits of OPCs may take a while to occur. This may be the case for health concerns resulting from everyday wear and tear, where time simply has taken its toll. Taking Isotonix OPC-3 daily enables the body to sustain a consistent antioxidant defense.
What is the advantage of taking Isotonix OPC-3 regularly?
OPC-3 not only provides the most potent OPCs available, the unique Isotonix delivery system ensures that the small intestine rapidly absorbs the OPCs, which are available in the blood stream within minutes. This is because the OPCs are delivered in liquid form. The liquid is isotonic, which means it duplicates the environment in our cells and blood stream regarding pH, electrolytes, etc. This enables the OPCs to enter the body easily and with a high level of bioavailability. Because of the rapid absorbability, the body should benefit from Isotonix OPC-3 almost immediately.
Why should everyone take Isotonix OPC-3?
Everyone is subject to free radical damage and oxidative stress. Free radicals develop as byproducts of physiological processes that occur within the body. This damage does not cause noticeable harm at first, yet may add up over the years. This process is largely responsible for the aging process. Free radicals have been linked directly to premature aging, poor circulation, poor heart health and poor immune health. OPCs are the most powerful natural free radical neutralizers and you get the best of all OPCs by taking Isotonix OPC-3. Regular use every day is vital for keeping free radicals in check and a long, healthy life. Laboratory studies have shown that OPCs are more powerful antioxidants than vitamin C and vitamin E.
Can you take Isotonix OPC-3 in soda, juice, coffee, etc., rather than water?
It is possible but not recommended. This product should only be taken as directed. In order to keep the product in an isotonic form and to achieve the maximum delivery speed, it needs to be taken on an empty stomach with 2 oz. of water per capful. Mixing the products with anything else besides other Isotonix products and water slows down the delivery time and may affect the percentage of uptake.
I am healthy and athletic, why should I take Isotonix OPC-3?
Everyone is vulnerable to the aging process caused by continuous free radical damage. Athletes tend to be exposed to elevated levels of oxidative stress. Free radicals develop as byproducts during metabolism when calories are processed with oxygen. Athletes inhale 10 to 20 times more oxygen during physical activity over rest periods. The increase in activity creates additional free radicals. In fact, these free radicals are known to limit performance, as free radicals appear to take their toll on muscle tissue. Studies on recreational athletes have shown a 20 percent endurance increase with OPCs, as compared to a control group receiving a placebo. Another study has shown that athletes using OPCs suffered significantly less muscle cramping during and after performing. Isotonix OPC-3 helps to maintain healthy blood flow and this supports oxygen supply to muscles.
Does OPC-3 have a rejuvenating effect?
The damage caused by free radicals adds up with time. A cause for more worry is the fact that your body's own mechanisms to keep free radicals in check decline with increasing age — when you need them the most. Suddenly, we find ourselves confronted with some typical age-related problems. Some cells of our body are more vulnerable to free radicals than others. OPC-3 has the ability to go in and do a knockout job, cleaning and scavenging the free radicals that feast on cellular energy, and take it away from vital processes.
What exactly is Pycnogenol?
Pycnogenol is the registered trademark of Horphag Research (UK) Ltd. for a standardized extract of bark of the French maritime pine tree. Pycnogenol is particularly renowned for its extensive clinical research with more than 120 studies published in peer-reviewed medical journals. The flavonoids in Pycnogenol not only act as powerful antioxidants, they also appear to promote the normal generation of nitric oxide (NO). NO plays a key role in regulating cardiovascular health. Nitric oxide promotes the normal relaxation of arteries, supports normal diameter of blood vessels and supports helps maintain healthy blood pressure and circulation. NO promotes normal platelet activity allowing the blood to maintain a normal, fluid viscosity. Pycnogenol has been awarded various patents for its ability to support healthy platelet activity.
How do I take OPC-3?
Each capful of Isotonix OPC-3 contains 125 milligrams of bioflavonoids, of which 75 milligrams are oligomeric proanthocyanidins in an isotonic-capable base. That means that the OPC-3 active ingredients will be delivered in the highest concentration to the small intestine, where most absorption of nutrients occurs.
To start using Isotonix OPC-3 for its benefit as an antioxidant and free radical scavenger, take two level capfuls for every 150 pounds of body weight for the first seven days. This is referred to as the saturation serving. Then, switch to a daily serving of one capful, per 150 lbs. of body weight, as a maintenance dose. For example, if you weigh 190 pounds, you would take three servings of Isotonix OPC-3 per day for seven days, and then switch to two servings per day for long-term health maintenance. This product should be taken on an empty stomach for the fastest, most effective delivery of the active ingredient.
What is the history of OPCs?
In 1534, French explorer Jacques Cartier was leading an expedition up the St. Lawrence River. Trapped by bad weather, Cartier and his crew were forced to survive on a ration of salted meat and biscuits. Cartier's crew began to suffer from severe deficiency of vitamin C and showed symptoms of scurvy. Many crew members died before the surviving members encountered a friendly Native American who saved most of their lives. He told them to make a tea from the bark and needles of the pine tree to cure their malady. They complied and, as a result, Cartier and many crew members survived.
Some 400 years later, Professor Jacques Masquelier of the University of Bordeaux, France, read a book by Cartier detailing their expedition. He concluded that pine bark not only contained some vitamin C, but obviously was a good source of bioflavonoids, whose effects are similar to those of vitamin C. Further studies and research revealed that the pine bark contained an array of proanthocyanidins complexes. These compounds were also found in a variety of plants, including grape seeds, cranberries, peanut skin, lemon tree bark and citrus rinds. Masquelier termed the active ingredients of the pine bark "pycnogenols", which today are referred to in the scientific community as oligomeric proanthocyanidins, or OPCs.
Science
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- Devaraj, S., et al. Supplementation with a pine bark extract rich in polyphenols increases plasma antioxidant capacity and alters the plasma lipoprotein profile. Lipids 37:931-4, 2002.
- Fine, AM, Oligomeric proanthocyanidin complexes: history, structure, and phytopharmaceutical applications. Altern Med Rev 5:144-51, 2000.
- Fitzpatrick, D., et al. Endothelium-dependent vascular effects of Pycnogenol. Journal of Cardiovascular Pharmacology 32: 509-515, 1998.
- Frankel, E., et al. Inhibition of oxidation of human low-density lipoprotein by phenolic substances in red wine. Lancet 341: 454-7, 1993.
- Freedman, J., et al. Select flavonoids and whole juice from purple grapes inhibit platelet function and enhance nitric oxide release. Circulation 103:2792-8, 2001.
- Frémont, L. Biological effects of resveratrol. Life Sciences 66: 663-673, 2000.
- Gulati, O. Pycnogenol® in venous disorders: a review. European Bulletin of Drug Research 7: 1-13, 1999.
- Hosseini, S., et al. Pycnogenol® in the management of asthma. Journal of Medicinal Food 4: 201-209, 2001. HHHh
- Kohama, T., et al. The treatment of gynecological disorders with Pycnogenol®. European Bulletin of Drug Research 7: 30-32, 1999.
- Kohama, T., et al. Analgesic efficacy of French maritime pine bark extract in dysmenorrhea. Journal of Reproductive Medicine 49: 828-32, 2004.
- Liu, X., et al. Antidiabetic effect of Pycnogenol French maritime pine bark extract in patients with diabetes type II. Life Sci 75:2505-13, 2004.
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- Maritim, A., et al. Effects of pycnogenol treatment on oxidative stress in streptozotocin-induced diabetic rats. J Biochem Mol Toxicol 17:193-9, 2003.
- Miyagi, Y., et al. Inhibition of human low-density lipoprotein oxidation by flavonoids in red wine and grape juice. Am J Cardiol 0:1627-31, 1997.
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- Nuttall SL, Kendall MJ, Bombardelli E, Morazzoni P. An evaluation of the antioxidant activity of a standardized grape seed extract, Leucoselect. J Clin Pharm Ther 23: 385-89, 1998.
- Packer, L., et al. Antioxidant activity and biologic properties of a procyanidin-rich extract from pine (Pinus maritima) bark, pycnogenol. Free Radic Biol Med 27:704-24, 1999. Review.
- Rohdewald, P. A review of the French maritime pine bark extract (Pycnogenol®), a herbal medication with a diverse clinical pharmacology. Int J Clin Pharmacol Ther 40:158-68, 2002. Review.
- Rohdewald, P. Pycnogenol®. In "Flavonoids in Health and Disease". Ed. Catherine Rice-Evans and Lester Packer. New York: Marcel Dekker, Inc., 1998. 405-19.
- Roseff, S., et al. Improvement in sperm quality and function with French maritime pine tree bark extract. Journal Reproductive Medicine 47: 821-4, 2002.
- Roseff, S., et al. Improvement of sperm quality by Pycnogenol®. European Bulletin of Drug Research 7: 33-6, 1999.
- Saito, M., et al. Antiulcer activity of grape seed extract and procyanidins. J Agric Food Chem 46: 1460-4, 1998.
- Schönlau, F., et al. Pycnogenol® for diabetic retinopathy. International Ophthalmology 24: 161-171, 2002.
- Schönlau, F., et al. The cosmeceutical Pycnogenol®. J Appl Cosmetology 20: 241-6, 2002.
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- Shi, J., et al. Polyphenolics in grape seeds-biochemistry and functionality. J Med Food 6:291-9, 2003. Review.
- Sharma, S., et al. Pycnogenol® inhibits the release of histamine from mast cells. Phytotherapy Research 17: 66-69, 2003.
- Spadea, L., et al. Treatment of vascular retinopathies with Pycnogenol®. Phytotherapy Research 15: 219-23, 2001.
- Stein, J., et al. Purple grape juice improves endothelial function and reduces the susceptibility of LDL cholesterol to oxidation in patients with coronary artery disease. Circulation 100:1050-5, 1999.
- Ueda, T., et al. Preventative effect of natural and synthetic antioxidants on lipid peroxidation in the mammalian eye. Ophthalmic Res 28: 184-92, 1996.
- Wallerath, T., et al. Resveratrol, a polyphenolic phytoalexin present in red wine, enhances expression and activity of endothelial nitric oxide synthase. Circulation 106:1652-8, 2002.
- Watson, R. Pycnogenol® and cardiovascular health. Evidence-Based Integrative Medicine 1: 27-32, 2003.
- Wei, Z., et al. Pycnogenol enhances endothelial cell antioxidant defense. Redox Report 3: 219-24, 1997.
- Yamakoshi, J., et al. Proanthocyanidin-rich extract from grape seeds attenuates the development of aortic atherosclerosis in cholesterol-fed rabbits. Atherosclerosis 142:139-149, 1999.
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Reviews
Displaying 1 - 5 of 182
01/19/2024
by Pahrin AS
AWESOME
My every morning go to product.
Response from Customer Service
01/19/2024
Dear Valued Customer,
Thank you so much for your awesome review! We are thrilled to learn that Isotonix OPC-3® has become an essential part of your morning routine. Your satisfaction is our top priority, and it warms our hearts to know that our product is making a positive impact on your daily life.
Thank you again!
The Product Information Team
09/22/2023
by WINNERC
Helped with complexion
Initially tried this for mestrual health, then it helped with my skin complexion as well. highly recommend!
07/22/2023
by AliciaD
Amazing product!
I am blown away with the health benefits of this product. I recommend this product to anyone that needs an overall supplement that can deliver results whether you are on medication or not you will feel your best everyday.
Response from Customer Service
07/24/2023
Dear Valued Customer,
Thank you for taking the time to share your thoughts on the Isotonix OPC-3®! We are so happy to hear you are pleased with the product!
Thank you again!
The Product Information Team
06/08/2023
by JudyG
Too many benefits to list!
I have been taking OPC-3 for close to 20 years. I truly believe there are benefits of the benefits with this product. Everyone needs the power of pycnogenol.
Response from Customer Service
06/09/2023
Dear Valued Customer,
Thank you for taking the time to share your thoughts on the Isotonix OPC-3®! We are so happy to hear you are pleased with the product!
Thank you again!
The Product Information Team
05/08/2023
by KENRICK YEE SAMT
this is awesome!!!
my skin complexion got so much better after taking this for months.
Response from Customer Service
05/11/2023
Dear Valued Customer,
Thank you for your positive feedback on the Isotonix™ OPC-3™ Plus. We are glad that you are happy with our product.
Thank you.
Shop.com Team
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